Fluspirilene
A dopamine inhibitor and calcium channel protein inhibitor
A dopamine inhibitor and calcium channel protein inhibitor
inhibitor of STAT3 and JAK-2 protein tyrosine kinase
Adenosine triphosphatase inhibitor
Serine/Threonine Kinase Inhibitors
GLI antagonist that inhibits GLI1-induced transcription (IC50 = 5 µM). Inhibits the hedgehog (Hh) signaling pathway downstream of SMO and SUFU causing GLI1 nuclear accumulation. Displays antiprolifera
tive and antitumor activity in vivo.
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pyrimidine antimetabolite
DBH [dopamine ß-hydroxylase] inhibitor
inhibits kinase activity of ATM / ATR
A cell-permeable, potent, selective and ATP-competitive ATM inhibitor