Out of stock

SB 415286

Serine/Threonine Kinase Inhibitors

GANT 58

GLI antagonist that inhibits GLI1-induced transcription (IC50 = 5 µM). Inhibits the hedgehog (Hh) signaling pathway downstream of SMO and SUFU causing GLI1 nuclear accumulation. Displays antiprolifera

tive and antitumor activity in vivo.

MSDS HS2-B018

CoA HS2-B018