Di-4-pyridinamine
GANT 58
GLI antagonist that inhibits GLI1-induced transcription (IC50 = 5 µM). Inhibits the hedgehog (Hh) signaling pathway downstream of SMO and SUFU causing GLI1 nuclear accumulation. Displays antiprolifera
tive and antitumor activity in vivo.
Benzo[1,2-c:3,4c´:5,6c´´]trithiophene
New Electron-Donating Units